Abstract: This paper describes the development of applications in the frame of the ATMOSPHERE platform. ATMOSPHERE provides means for developing container-based applications over a federated cloud offering measuring the trustworthiness of the applications. In this paper we show the design of a transcontinental application in the frame of medical imaging that keeps the data at one end and uses the processing capabilities of the resources available at the other end. The applications are described using TOSCA blueprints and the federation
of IaaS resources is performed by the Fogbow middleware. Privacy guarantees are provided by means of SCONE and intensive computing resources are integrated through the use of GPUs directly mounted on the containers.